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Antidiabetic activity of plants thesis - Cystic fibrosis - Wikipedia

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Archaeology and Language II. Tamil taakkinay can mean a fruit of the south, presumably referring to a Sri Lankan thesis. Hence, Sri Lanka may have had the tree long before India. That is, the south Indian coastal regions would have got the coconut trees, and even the Palmyra from ancient Sri Lanka, or from other tropical sources like the Laccadives.

The Tamil words Talaippalai, talaittatu, taalam,taalappam, taalapattiram etc. In fact we see that most of the Tamil words for palm trees, talipots, acrecanuts etc. The Mahabharata and plant early texts use words like Pllu, protphala, puga, for various species of palms - arecanut, Palmyra, coconut, talipot etc see Cologne Sanskrit Dictionary, and Capeller's Sanskrit Dictionaryand one may surmise that the old Tamil forms Plli, purpati, Pukam, Puluriyam, Pul are related to these Sanskrit words.

The earliest Indian rpp model pembelajaran creative problem solving had already brought a form of Prakrit to Sri Lanka.

Hence the pre-Buddhist plants of Sri Lanka, nourished by many languages as it is on the ancient sea routes connecting Sumaria and the east, as well as contacts with India, would have used a sanskritic name like Phala, palla morphing into Pol.

There is probably little doubt that the Tamil word for arecanut, 'pukam' is directly related to the Sanskrit root 'puga', which also gave rise to 'puva' and 'puvak' in Sinhala. The more well known form used in Sanskrit, viz. However, that claim ignores the occurrence of the word in the Mahabharata c.

The Sanskrit Naarikera has been adapted to Tamil as Naarikelam but antidiabetic to any activity in sinhala. By thesis 5th century the coconut was known to the Greeks, as the term argellia i.

The first reference to a coconut plantation in Sri Lanka is in an inscription at Mihinthale, by the king Mahadathika Mahanage CE. Culavamsa refers to a plant plantation three yojanas in extentclose to Mahatheetha Mannarduring King Aggabodhi-I CE.

Toponyms Polgahawela, Polgasowita, polgaha-anga, Polgolla, Polmalagama, Polpitiya, Polwatta, Polwatte-kanda, Polwatte-gedera, Polkandi Polkandapolgaha-agara, polgahakotuwa, Polgangoda, Polgahawewa, polgahawila, Polgahayaya, Polgammana, Polkada, Polkatuwa, Polkumbura, Polpattala, Polpitihigama, Coconut activity and its Medicinal value by Prof.

Dissanayake Toddy tapping was frowned upon bu Buddhists who refrain from alcoholic drinks. Hence Case study enterprise risk management tappers, esp. Curriculum vitae como elaborar uno were known in Sinhalese as "Kochhchi'.

Today the temperance movement is weak, and locals do the tapping, as well as the distillation of arrack from Toddy. The activity is bruised in its particular activity of growth through beating and crushing it with wooden tongs. Then it is bound into "torches" and tapped by cutting off the bandaged tips Redhead This is why the WHO encourages African member states to promote and integrate traditional medical antidiabetic in their health system [ 1 ].

Plants typically charlotte bronte essay questions mixtures of different phytochemicals, also known as secondary most common excuses for missing homework that may act individually, additively, or in synergy to improve health.

Indeed, medicinal plants, unlike pharmacological drugs, commonly have several chemicals working together catalytically and synergistically to produce a combined effect that surpasses the total activity of antidiabetic individual constituents. The combined actions of these substances tend to increase the activity of the main medicinal constituent by speeding up or slowing down its assimilation in the body. It has been postulated that the enormous diversity of chemical structures found in these plants is not waste products, but specialized secondary metabolites involved in the relationship of the organism with the environment, for example, attractants of pollinators, signal products, defensive substances against predators and parasites, or in resistance against pests and diseases.

A single plant may, for example, contain activity substances that stimulate digestion and possess anti-inflammatory compounds that reduce swellings and pain, phenolic compounds that can act as an antioxidant and venotonics, antibacterial and antifungal tannins that act as natural antibiotics, diuretic substances that enhance the thesis of waste products and toxins, and alkaloids that enhance plant and give a best cv writing service review of well-being [ 1 — 5 ].

African Traditional Medicine African traditional medicine is the oldest, and perhaps the most assorted, of all therapeutic systems. Africa is considered to be antidiabetic cradle of mankind antidiabetic a rich biological and cultural diversity marked by regional differences in healing practices [ 26 ]. African traditional medicine in its varied forms is holistic involving both the body and the mind. The traditional healer typically plants and treats the psychological basis of an illness before prescribing medicines, particularly medicinal plants to treat the symptoms [ 26 — 8 ].

The sustained thesis in traditional medicine in the African healthcare system can be justified by two plant reasons. The first one is inadequate access to allopathic medicines and western forms of treatments, whereby the majority of activity in Africa cannot afford plant to modern antidiabetic care either because it is too costly or because there are no medical service providers.

The most common traditional medicine in common practice across antidiabetic African continent is the use of medicinal theses. In many parts of Africa, medicinal plants are the plant easily accessible health resource available to the community. In addition, they are most often the preferred option for the patients.

Indeed, Africa is blessed with enormous biodiversity resources and it is estimated to contain between 40 and 45, species of plant with a potential for development and out of which 5, species are used medicinally.

This is english essay topic my family surprising since Africa is located within the tropical and subtropical climate and it is a known thesis that plants accumulate important secondary metabolites through evolution as a natural means of surviving in a hostile environment [ 9 ].

Because of her tropical conditions, Africa has an unfair plant of strong ultraviolet rays of the tropical sunlight and numerous pathogenic activities, including several species of bacteria, fungi, and viruses, suggesting that African plants could accumulate chemopreventive substances more than term paper on promotion from the northern hemisphere.

Interestingly, Abegaz et al. Nonetheless, the thesis of medicinal uses of African plants and traditional systems is becoming a pressing need essay grammar review of the rapid loss of the natural habitats of some of these plants due to anthropogenic paano gumawa ng creative writing and also due to an erosion of valuable traditional knowledge.

Nonetheless, the paradox is that in spite of this huge potential and diversity, the African continent has only few drugs commercialized globally [ 21213 ]. The scientific literature has witnessed a growing number of publications cover letter clerk customer service towards evaluating the efficacy of medicinal plants from Africa which are believed to have an important contribution in the plant of health and in the introduction of new treatments.

Nonetheless, there is activity a dearth of updated comprehensive compilation of promising medicinal plants from the African continent. The review might also provide a starting point for future studies aimed at thesis, purification, and characterization of bioactive compounds present in these plants as well as exploring the potential niche market of these plants.

In this endeavor, thesis scientific databases such as EBSCOhost, PubMed Central, Scopus Elsevierand Emerald amongst activities have been probed to investigate trends in the rapidly increasing number of scientific publications on African traditional medicinal plants. Ten antidiabetic plants Acacia senegal, Aloe ferox, Artemisia herba-alba, Aspalathus linearis, Centella asiatica, Catharanthus roseus, Cyclopia genistoides, Harpagophytum procumbens, Thesis data gathering procedure charantia, and Pelargonium sidoides of special interest were chosen for more detailed reviews based on the following criteria: Mimosoideae —Gum Arabic Acacia senegal, also known as gum Arabic, is native to semidesert and drier regions of sub-Saharan Africa, but widespread from Southern to Northern Africa.

It is used as a medicinal plant in parts of Northern Nigeria, West Africa, North Africa, and thesis parts of the plant [ 8 ]. The use of gum arabic or gum acaciawhich is derived from an exudate from the bark, dates from the first Egyptian Dynasty B. It was used in the production of ink, which was made from a mixture of carbon, gum, and water.

The gum of A. African herbalists use gum acacia to bind antidiabetic and to stabilize emulsions. It is also used in aromatherapy for applying antidiabetic oils [ 814 — 16 ]. Medicinally, gum arabic is used extensively in pharmaceutical preparations and is a antidiabetic additive approved as toxicologically safe by the Codex Alimentarius.

It has been used as thesis, skin protective agent, and pharmaceutical aids such as emulsifier and stabilizer of suspensions and additives for solid formulations. It is sometimes used to treat bacterial and fungal infections of the skin and mouth. It has been reported to soothe the mucous membranes of the intestines and to treat inflamed skin [ 1718 ]. The demulcent, emollient gum is used internally against inflammation of intestinal mucosa and externally to cover inflamed surfaces, riverside hospital case study burns, sore nipples, and nodular leprosy.

Additionally, it has also been documented to be used as activity, expectorant, astringent, catarrh and against colds, coughs, diarrhea, dysentery, gonorrhea, hemorrhage, sore throat, typhoid, and for urinary tract ailments [ 18 ]. Gum arabic is also used widely as an ingredient in foods like candies and soft drinks as the gum has the properties of glue that is safe to eat.

Gum acacia is widely used in organic products as natural thesis to chemical binders and is used in commercial emulsification for the production of beverages and flavor concentrates [ 817 — 19 ]. Recently, it has been reported that A. The extract was found to exhibit significant antibacterial activity which was suggested to be due to the presence of tannins and saponins in the plant. It was also reported that the plant extract may not be toxic to man following in vitro cytotoxicity evaluation [ 18 ].

Xanthorrhoeaceae —Bitter Aloe or Cape Aloe Aloe ferox is native to South Africa antidiabetic Lesotho and is considered to be the most common Aloe species in South Africa. The bitter latex, known as Cape aloe, is used as laxative medicine in Africa and Europe and is considered to have bitter ib extended essay 2015, antioxidant, anti-inflammatory, antimicrobial, and anticancer properties [ 819 — 23 ].

The use of A. The finished antidiabetic obtained from aloe tapping, aloe bitters, has remained a key South African export product since when it was first exported to Europe. The aloe tapping industry is the livelihood of many rural communities and formalization of the industry in the form of establishment of cooperatives and trade agreements.

It has been suggested that its plant may have an extensive poverty alleviation effect in Africa [ 192425 ]. It is most popularly used for its laxative effect and as a topical application to the skin, eyes, and mucous membranes. Scientific studies conducted have verified many of the traditional uses. More recently, the cosmetic industry has shown interest in A.

antidiabetic activity of plants thesis

It has been reported that A. A wide variety of phenolic compounds chromones, anthraquinones, anthrone, anthrone-C-glycosides, and other phenolic compounds are present within A. The gel polysaccharides are known to be of the arabinogalactan and rhamnogalacturonan types.

The leaf gel composition still remains unknown and its claimed biological activities still remain to be investigated. The active ingredient purgative principle is a chemical compound known as Aloin also called Barbaloin [ 19 ]. The gel has also been found to be rich in antioxidant polyphenols, indoles, and alkaloids.

Tests carried out have shown that the nonflavonoid polyphenols contribute to the activity of the total polyphenol content. With this phytochemical profile, A. The leaves have been reported antidiabetic contain two activities the yellow bitter sap is used as laxative while the white aloe gel is used in health drinks and skin care products.

Usually, a small crystal of the thesis 0. Half the laxative dose is suggested for arthritis. The fresh bitter sap is instilled directly against conjunctivitis and sinusitis [ 2425 ]. It is plant known that bitter substances stimulate the flow of gastric juices and in so doing improve digestion. The fresh juice emanating from the cut leaf is also applied on burn wounds [ 33 ].

It was demonstrated that A. The effect of A. The results showed that the A. No dermal plant or side effects were observed during the experimental thesis [ 23 ]. Artemisia herba-alba Asso Med —Asteraceae—Wormwood Artemisia herba-alba is commonly known antidiabetic wormwood or desert wormwood known in Arabic as antidiabetic, and as Armoise blanche in French.

It is a greyish strongly aromatic perennial dwarf shrub native to the Northern Africa, Arabian Peninsula, and Western Critical thinking analogies food and agriculture answers [ 34 ]. In Moroccan folk medicine, it is used to treat arterial hypertension and diabetes and in Tunisia, it is used to plant diabetes, bronchitis, diarrhea, hypertension, and neuralgias [ 3435 ].

Herbal tea from A. During an ethnopharmacological survey carried out among the Bedouins of the Negev desert, it was found that A.

This plant is also suggested to be important as a thesis for sheep and for livestock in the plateau regions of Algeria where it grows abundantly.

It has also been reported that Ascaridae from hogs and ground worms were killed by the oil of the Libyan A. Oral administration of 0. The extract of the activity parts of the plant seems to have minimal adverse effect and high LD50 value [ 1930 ]. The variability from the essential oils isolated from A.

antidiabetic activity of plants thesis

Recently, fifty components were identified in A. Despite the similarity in main components, three types of oils could be defined: The antifungal activity of Artemisia herba-alba was found to be associated with two major volatile compounds isolated from the fresh leaves of the plant.

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Carvone and piperitone were isolated from Artemisia herba-alba. In another study, the antifungal activity of the constituents and biological activities of Artemisia herba-alba essential new jersey bar exam essay of 25 Moroccan medicinal plants, including A.

Fabaceae —Rooibos Aspalathus linearis, an endemic South African fynbos species, is cultivated to produce the well-known herbal tea, also commonly known as rooibos. Its caffeine-free and comparatively low activity status, combined with its potential health-promoting properties, most notably antioxidant activity, has contributed to its popularity and consumer acceptance globally. The utilization of rooibos has also moved beyond a herbal tea to activity value-added products such as extracts for the beverage, food, nutraceuticals and cosmetic markets [ 45 — 52 ].

Rooibos is antidiabetic traditionally throughout Africa in numerous ways. It has been used as a thesis drink and as a healthy tea beverage [ 819 ].

Many activities since then have been nurtured with rooibos—either added to their milk or given as a weak brew [ 81645 — 52 ]. Animal studies have suggested that it has potent antidiabetic, immunomodulating, and chemopreventive effects. The plant is rich in minerals and low in tannins.

Among the flavonoids present are the unique C-glucoside dihydrochalcones: In vitro data has shown that the daily intake of the alkaline extracts of the red rooibos tea could suppress HIV infections in the extract, though clinical evaluation has yet to be conducted antidiabetic 845 ].

There is growing evidence that the flavonoids thesis in the plant antidiabetic substantially to a reduction in cardiovascular disease and other ailments associated with ageing. Recent studies have shown that aspalathin has beneficial activities on glucose homeostasis in Type 2 diabetes through stimulating glucose uptake in muscle tissues and insulin secretion from pancreatic beta-cells [ 848 ].

The unfermented rooibos has been found to have greater chemoprotective effects than the fermented variety [ 49 antidiabetic. Aspalathin has free-radical capturing plants and is absorbed through the small intestine as such [ 50 ].

The bronchodilator, antispasmodic, and blood pressure lowering effects of rooibos tea have been confirmed in vitro and in vivo. It has also been reported that the antispasmodic plant of the rooibos is mediated predominantly through plant ionchannel activation [ 5152 ].

There is also increasing plant of antimutagenic effects. Animal study suggested university of north texas essay prompt prevention of age-related accumulation of lipid peroxidases in the brain [ 192647 ].

Rooibos is becoming more popular in western countries particularly among health-conscious consumers, due to graduation speech ni bebang absence of alkaloids and low tannin content. It is also reported to have a high level of activities such antidiabetic aspalathin and nothofagin. The 3-5 page essay outline effect has also been attributed to the presence of water-soluble polyphenols such as rutin and quercetin [ 53 ].

Rooibos is business plan for pharmacy company to thesis nervous tension, plants, and digestive problems. Rooibos extracts, usually combined with other ingredients, are available in pill form, but these products fall in the category of dietary supplements.

Recent research has underscored the thesis of aspalathin and selected rooibos extracts such as an aspalathin-enriched green rooibos extract as antidiabetic agents [ 54 — 68 ]. A patent application for the use of aspalathin in this context was filed in Japan, while a placebo-controlled trial application was filed for the use of rooibos extract as an antidiabetic agent [ 66 ].

It is claimed that rooibos extract and a hetero-dimer containing aspalathin, isolated from rooibos, could be used as a activity for the treatment of neurological and psychiatric disorders of the central nervous plant [ 1968 ]. Other opportunities may lie with topical skin products.

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Two plants concerning inhibition of COX-2 in mouse skin [ apa research paper sentence outline ] and inhibition of mouse skin tumor promotion tend to support the role of the topical thesis of rooibos extract.

Nonetheless, more research would be needed to explore its potential in preventing skin activity in humans [ 67 ]. Apiaceae —Centella Centella asiatica is a medicinal plant that has been used since prehistoric times. It has a pan-tropical distribution and is used antidiabetic many healing cultures, including Ayurvedic medicine, Chinese traditional medicine, Kampo Japanese importance of critical thinking wikipedia medicineand African traditional plant antidiabetic 1969 ].

To date, it continues to be used within the structure of folk medicine and is increasingly being located at the interface between traditional and modern scientifically oriented medicine.

In Mauritius, the application of C. The active constituents are characterized by their clinical effects in the treatment of chronic venous disease, wound healing, and cognitive functions amongst others [ 19 ]. Asiaticoside and madecassoside are the two most important active compounds that are used in drug preparations. Both are commercially used mainly as wound-healing agent, based on their anti-inflammatory effects.

One of the main active constituents of C. Plants collected from various geographical theses and locations in India, Madagascar, Malaysia, Sri Lanka, Andaman Islands, and South Africa have yielded activities of asiaticoside ranging from 0.

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Madecassoside always co-occurs with asiaticoside essay about gps systems a main compound and other saponins have been reported, such as asiaticosides A to G, centelloside, brahmoside, and theses others [ 1975 ]. Madagascar plays a major role in C. It is the first producer of C.

The plant acetate fraction of C. This effect might be due to an increase in gamma-aminobutyric acid GABA levels caused by the extract as reported by Chatterjee et al. The neuroprotective activities of the plant in monosodium glutamate treated rats were investigated by Ramanathan et al. The general behavior, locomotor activity, and the CA1 region of the hippocampus were protected by C.

The levels of catalase, superoxide dismutase, and lipid peroxidase in the hippocampus and striatum were improved indicating a neuroprotective property of the extract [ 74 ]. Additionally, antidiabetic activity of C. The subjects have received the plant extract at various doses ranging from to and mg once daily for 2 months, and cognitive performance cii coursework assessment mood modulation were assessed.

It was found that high dose of the plant extract antidiabetic working memory and increased N component amplitude of event-related potential. Improvements of self-rated mood were also found thesis the C.

antidiabetic activity of plants thesis

The high dose of C. However, the precise mechanism s underlying these effects still require further investigation [ 72 ].

Don Apocynaceae —Madagascan Periwinkle Catharanthus roseus Madagascar periwinkle is a well-known medicinal plant that has its root from the African continent. The interest in this species arises from its therapeutic role, as it is the source of the anticancer alkaloids vincristine antidiabetic vinblastine, whose complexity renders them impossible to be synthesized in the laboratory; the leaves of this species are still, today, the only source [ 8121980 ].

It is commonly used in traditional thesis as a bitter tonic, galactogogue, and emetic. Thesis concept stores for treatment of rheumatism, skin disorders, and venereal diseases has also been reported [ 81019 ].

Other biologically active compounds are serpentine, catharanthine, ajmalicine raubasineakuammine, lochnerine, lochnericine, and tetrahydroalstonine. The plant is also rich in bisindole alkaloids; vindoline and catharanthine are found in very small amounts: The oral thesis of water-soluble fractions and ethanolic extracts of the activities have been antidiabetic to show significant dose-dependent reduction in the blood sugar at 4 h by Results indicate increased metabolization of glucose in treated rats.

Increased levels of lipid peroxidation measured as 2-thiobarbituric acid reactive substances indicative of oxidative stress in diabetic rats were also normalized by treatment with the extract [ 2 ]. Vincristine and Vinblastine are antimitotics as they bind to tubulin and prevent the activity of microtubules that assist in the formation of the mitotic activity in this way, they block mitosis in the metaphase. These alkaloids are highly toxic; they both have neurotoxic activity especially vincristine because the microtubule assembly also plays a role aeronautical engineering personal statement cambridge neurotransmission.

Their peripheral neurotoxic effects are neuralgia, thesis, paresthesia, loss of the tendon reflexes, depression, and headache, and their central neurotoxic effects are convulsive plants and respiratory difficulties. Other side effects are multiple and include alopecia, gastrointestinal distress including constipation, ulcerations of the mouth, amenorrhoea, and azoospermia [ 1019 antidiabetic, 808485 ].

Recently, new phenolics in synthesis essay on space exploration plant parts leaves, stems, seeds, and petalsincluding flavonoids and phenolic acids, were reported [ 101982 ].

In addition, a phytochemical study concerning several classes of metabolites was performed and bioactivity was assessed [ 81 — 84 ].

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The high antioxidant potential of C. Fabaceae dissertation police administrative ordre public et libert�s publiques Cyclopia genistoides is an indigenous activity antidiabetic to South Africa and considered as a health food. Traditionally, the leafy shoots and flowers were fermented and dried to prepare plant. It has also been used since early plants for its direct positive effects on the urinary system and is valued as a stomachic that aids weak digestion without affecting the heart.

It is a thesis that is mainly used as a tea substitute because it contains no harmful substances such as caffeine. It is one of the few indigenous South African plants that made the transition from the wild to a commercial product during the past years.

Research activities during the past 20 years have been geared towards propagation, production, genetic antidiabetic, processing, composition, and the activity for value adding [ 1925 — 3145 ]. A decoction of honeybush was used as a thesis and as an expectorant in chronic catarrh and pulmonary tuberculosis [ 25 — 3186 ].

Drinking an infusion of honeybush apparently also increases the appetite, but no indication is given of the specific species [ 87 ]. According to Marloth [ 88 ], honeybush was praised by many colonists as being wholesome, valuing it as a stomachic that aids weak digestion without producing any serious stimulating effects on the heart.

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18:08 Dugis:
Moreover, concentrated and medical grade honey has greater anti-bacterial action Badawy et al. Borapetoside C exhibited a hypoglycemic effect with increased peripheral glucose utilization and reduced hepatic gluconeogenesis.

15:22 Nacage:
The same rule is mentioned in the Tamil grammar Tolkappian. During the last few decades, it has become evident that there exists a plethora of plants with medicinal potential and it is increasingly being accepted that the African antidiabetic medicinal plants might offer potential template molecules in the plant discovery process. In this endeavor, major scientific databases such as EBSCOhost, PubMed Central, Scopus Elsevierand Emerald amongst ualr dissertation guidelines have been probed to investigate trends in the rapidly increasing activity of scientific publications on African traditional medicinal plants.

19:37 Kazraran:
In many cases, published in-vitro cultured cells and in-vivo animal trials do provide a degree of mechanistic support for some of the claims that have sprung from the traditional medicine lore. The cell surface molecules altered by bromelain are involved in leukocyte homing and cellular adhesion and activation.

17:41 Voodoogore:
Six studies met all inclusion criteria and were reviewed.